The Villa Necchi Campiglio was designed by Piero Portaluppi, who was one of the greatest Italian architects of the era. The villa is made in a nascent architectural style with large and bright rooms with excellent furnishings, decorative arts, and artifacts. The villa houses paintings from the 18th century to the early 20th century.

The Villa houses splendid collections by Alighiero de Micheli, a textile industrialist, and banker. There are more than 130 masterpieces from the 18th century including paintings, furniture, Lombard ceramics, and rare miniatures. The Princess’ room contains the collection curated by the architect Filippo Perego and Jean-Baptiste Isabey.

Make sure to visit the Claudia Gian Ferrari Collection that was given to FAI which includes 44 paintings, drawings, and sculptures. The collection is from early-twentieth-century Italian artists including Giacomo Balla, Umberto Boccioni, Filippo de Pisis, Carlo Carrà, Giorgio Morandi, Mario Sironi, and Adolfo Wildt.

Angelo’s Studio is one of the most precious study rooms of the villa. The studio perfectly depicts the historicity of the villa and its changing styles over the years. The design of the studio was revamped during the 1950s with Buzzi’s more ornate Art Nouveau. The rooms are decorated with antique furnishings, walnut floors, and wood-paneled siding.

The Boschi di Stefano veranda is the villa's most Instagrammable place, situated right next to the library. The tall and double pane glass windows offer splendid views of the lush gardens. The Veranda has exotic green marble tiles on the floor that accentuates its regal look.

Nedda Necchi’s Room is the most important part of the villa. Make sure to explore ​​Necchi’s collection of twentieth-century art pieces to the fullest. The intricate Milanese architectural elements of this room perfectly capture the aristocratic luxuries of Necchi's life.

The First floor is the central part of the Villa Necchi Campiglio, which is occupied by a large hallway. There are two main apartments on the right and wardrobe walls on the side of a corridor. The floor displays the Necchi sisters’ impressive collection of couture.

The mezzanine serves as a reception area and is paved in walnut and rosewood. On the left, there is a library with diamond-patterned stucco ceilings. The Gulemigo Ulrich gaming tables in the Mezzanine are now used for events and conferences.

The Fumoir is a small lounge in the villa refurbished by Buzzi. The Fumoir was highlighted with a large Renaissance-style fireplace. Next to the lounge, there is a dining room, and its walls are clad in vellum, and the stucco ceiling above is covered in astrological motifs.

The basement housed service rooms and large servants' quarters. It also included a pantry, a dining room for the servants, changing rooms, showers with original furnishings, and a billiard room. The dining room table is now used for events, photographic exhibitions, and conferences.